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The primary hypothalamic target for ghrelin are neurons in ARC that express and release NPY and AgRP in the lateral hypothalamus and LHA to mediate orexigenic effect in the brain (16, 17)
This is underscored by the results of a clinical trial comparing the development of obese adults who received either semaglutide or liraglutide in addition to nutritional advice and physical activity, and significantly greater weight loss was achieved in the semaglutide group [102]
Shes on a GLP-1 to manage obesity and cardiometabolic risk
